Product: Human-induced cortical neurons

Elpis cortical neurons are derived from hiPSCs by using the OPTi-OX system. Elpis has produced homogenous, controllable, and extremely high expression of inducible transgenes NGN2 hIPSCs. These cells, on addition of doxycycline, differentiate within days into pure, mature and functional cortical neurons. Elpis’ neurons are ready-to-culture, for research use. These neurons are suitable as models for research in cell-type specific biology, target validation and drug screening in pharmaceutical R&D, and screening for toxicology. Applications include functional and general neurotoxicity assays. Our cortical neurons are pure (>99%), easy to culture and ready for use without requiring cumbersome cell culture work. Batch-to-batch consistency has ensured that the cortical neurons have been successfully used in very demanding screening conditions where only small changes had to be picked up from background noise.

Advantages of Elpis cortical neurons

Highly pure population

Fast maturation

Early electrical signal

Easy culturing

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Production Specification

Catalogue no.: e0101a
Manufacture site: United Kingdom
Product code:
Size: 1x10^6 cells
Product use: iCONE1 are for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures
Storage: Upon receiving, directly and immediately transfer the cells from dry ice to liquid nitrogen and keep the cells in liquid nitrogen until they are needed for experiments
Shipping info: Dry Ice

Supported applications


  • Drug screens
  • Genetic screens
  • Chromatin immunoprecipitation
  • Patch clamp and EMA


Product Data

MEA recordings on day 11 - spontaneous activity detected

Picture 5 of 5


Documentation

Publication – Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes

Conference poster, BTS 2018 – Inducible, fast and reproducible differentiation of human pluripotent stem cells (hPSC) into neurons for neurotoxicity screening 

Webinar – What is the future of physiologically relevant cell models in neurology


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